Cardiotonic Drugs. Antiarrhythmic Agents - SlideShare.
Drugs that increase the contractile power of the myocardium and thus enhance its capability and efficacy are called cardiotonic agents. Cardiac insufficiency. can be defined as an inability of the heart to pump a sufficient amount of blood to supply oxygen and nutrients to organs and tissue, which leads to fatigue, shortness of breath, and edema.
Cardiotonic drugs are drugs, which increase cardiac contractile force during heart failure. Heart failure (HF) is a pathological state during which cardiac output is inadequate to provide the minute volume needed by the body or relatively normal minute volume and blood supply of the peripheral tissues is provided by the congested load of the heart.
CARDIOTONIC DRUGS. CARDIAC GLYCOSIDES AND OTHER INOTROPIC DRUGS. AGENTS USED FOR CONGESTIVE HEART FAILURE (Strophantinum, Corgliconum, Digoxinum, Digitoxinum, infusum herbae Adonodis vernalis, Dophaminum, Dobutaminum). Cardiotonic drugs. Cardiac glycosides and other inotropic drugs.
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Assignments, Chapter 44, Cardiotonic Agents Written Assignments Learning Objective(s) 1. Describe the pathophysiology of heart failure. What are the clinical signs and symptoms of heart failure? 2. Explain how the compensatory mechanisms for heart failure work to maintain cardiac function. What occurs if these mechanisms begin to fail? 3.
Cardiotonic agents- chapter 44. STUDY. PLAY. Congestive heart faliure. Condition in which the heart fails to effectively pump blood throughout the body. Primary treatment of CHF using cardiotonic agents. Allows the heart muscle to contract more efficiently in an effort to bring the system back into balance.
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Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Antihypertensive drugs have, then, never been more important. Along with diet and exercise, they remain one of the most effective methods to reduce high blood pressure. Antihypertensive Drug Classes. When we talk about the pharmacology of antihypertensive drugs, we’re talking about a very large and diverse family of medicines (see below).
The beta(1)-selective Adrenoceptor Agonist Dobutamine'': A Fallacy Being Perpetuated Waldeck, Bertil LU () 21st International Symposium on Chirality 23 (1). p.63-64. Mark; Abstract Dobutamine is a cardiotonic agent, developed as a racemate more than 30 years ago.
The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar and an R group. The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity.
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
Cardiotonic inotropic drugs, which are pharmacological agents that have a strengthening effect on the heart or that can increase cardiac output, represent the most frequent treatment for heart failure. Sometimes they are called positive inotropes; negative inotropes weaken the force of the heartbeat.
